Manual search through both national and international guidelines as well as relevant journals and publications on the topic has been also conducted. ConclusionOptimal asthma control, preventing, detecting, and treating the exacerbations are of the utmost importance to minimize the adverse effects for both the mother and fetus/neonate. Guidelines recommend active asthma management during pregnancy. Strong support prior and throughout the pregnancy and individualized treatment, guided by a multidisciplinary team, is suggested. Education on the importance of anti-asthmatic therapy, avoiding triggers, frequent and accurate monitoring are essential for good asthma management. Considering the pandemic, we are facing and the potential impact of COVID-19 on asthma, Global Initiative for Asthma (GINA) guideline recommendations for physicians are mentioned in the present article.Context At present, the method of practical assessment in pharmacology focuses on cognitive and subjective domains. Ideally, it should be objective and comprehensive. Objective To compare marks obtained in two types of exams, objective structured practical examination (OSPE) and traditional practical examination (TDPE), in order to assess faculty members' and students' perception of OSPE Methodology Sixty students having 75% attendance were included in the present study. Both OSPE and TDPE were conducted and marks obtained in each of the two exams were compared. Perceptions of students and faculty members were assessed on the basis of Likert- scale. Result and discussion The percentage of mean marks obtained in TDPE (67.5±2.24) was higher than in OSPE (66.5±2.78), but the results were not statistically significant (p=0.6). This may be due to first time exposure of OSPE and belief that marks would not be counted in internal assessment. Ninety five percent of students agreed that practical skills and knowledge acquired during OSPE would be also helpful after graduation, and 83.33% of participants admitted that personality, gender and other student-related factors did not affect scoring in OSPE. Eighty five percent of students and all faculties were willing to implement OSPE as an assessment tool. All faculties were in favour of OSPE due to its very low variability and because it motivated students learn skills as well subject more. ConclusionObjective structured practical examination is comparable to TDPE as assessment tool for pharmacology practical examination in terms of marks obtained by students, while satisfaction reported by faculties and students regarding various aspects of OSPE is much more in favour of the latter.Background Chronic low back pain (LBP) is the most common musculoskeletal condition affecting a person's quality of life. Over the past decades, a lot of work was done in an attempt to reduce the negative impact of LBP, and help patients recover and maintain a better quality of life. Nevertheless, there is still a lot to be done to fully understand the problem of underlying chronic LBP and a wide gap that exist between basic science and applied rehabilitation research on LBP. Objectives This was an open label, multicentric, observational, post-marketing surveillance study in a real-world setup designed to evaluate the efficacy and safety of MyrliMax® capsules containing standardised Commiphora myrrha gum resin extract in Indian subjects with chronic LBP varying in intensity. Materials and methodsThis study included 204 subjects diagnosed with chronic LBP at the outpatient department of 20 centres under the supervision of a medical doctor. All subjects took MyrliMax® capsules twice daily for 20 days. Visual AnionMyrliMax® capsule is a potentially effective and safe therapy for pain reduction in patients suffering from chronic LBP. MyrliMax® capsules can be used to reduce pain in NSAIDs intolerant subjects suffering from chronic LBP.Background Metabolic syndrome is a known risk factor for various diseases including coronary artery disease and is associated with subclinical-inflammation. Various inflammatory markers have been evaluated in metabolic syndrome. However, the data evaluating serum ferritin in metabolic syndrome is sparse. The current study aims to evaluate the correlation between serum ferritin and metabolic syndrome. Materials and methodsThis cross-sectional study included 100 subjects with metabolic syndrome and 50 gender matched healthy controls. ResultsThe mean age (SD) in study and control groups was 52.34 (7.64) and 48.36 (9.16) years, respectively. Majority were females in both groups (60% vs 52%). The mean (SD) HbA1c amongst study vs control was 8.26 (2.33) vs 5.10 (0.51); less then 0.0001. Mean (SD) serum iron and hsCRP were significantly higher in the study group (115.50 ±42.6 vs 65.741±9.16; p less then 0.001) and (6.33±4.87 vs 3.45±3.5; p less then 0.007) respectively. Mean serum ferritin level was significantly higher in the study group (123.9 vs 59.02; p less then 0.0001). A statistically significant correlation was found between serum ferritin and waist hip ratio, triglyceride, BMI and HOMA IR (r=0.49, p less then 0.0001; r=0.50, p less then 0.0001; r=0.47, p less then 0.0001 and r=0.54, p less then 0.0001 respectively). An inverse correlation was found between serum ferritin and serum HDL levels (r=-0.46, p less then 0.0001). Even after adjusting for age, serum ferritin levels were found to be significantly associated with metabolic syndrome Coeff (95% CI) -65.6 (-84.23, -46.98); p less then 0.0001. ConclusionSignificantly higher levels of serum ferritin were found in metabolic syndrome, and a significant correlation with its components was seen. Therefore, serum ferritin may be used as a marker of inflammation for an early intervention.Objectives Uncontrolled pain after cesarean delivery is associated with women's dissatisfaction and limited ability to take care of the neonate. https://www.selleckchem.com/products/iodoacetamide.html Materials and methodsThis prospective observational study included 173 women scheduled for elective cesarean delivery under spinal anesthesia. Postoperative analgesia included subcutaneous morphine 0.1 mg/kg in the post-anesthesia care unit, followed by intravenous paracetamol 1000 mg every eight hours and intravenous diclofenac 75 mg every 12 hours in the ward. Subcutaneous morphine was repeated on demand. Pain intensity at rest, pain intensity after movement and cumulative morphine consumption were recorded at 2, 4, 8, and 24 hours postoperatively. Acute pain intensity was assessed on a 100 mm visual analogue scale (VAS, score 0-100 mm). Three and six months postoperatively, women were interviewed by phone for the presence of persisting pain, abnormal sensation in the wound area and analgesic consumption. ResultsOur results showed that 24 hours postoperatively the mean dose of morphine was 16±7.